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human tlr7 dual reporter hek 293 cells  (InvivoGen)


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    Structured Review

    InvivoGen human tlr7 dual reporter hek 293 cells
    (A) Representative flow cytometry of Tfh cells, GC B cells, and Spike-specific GC B cells (S+) from wild type (WT) and Myd88 −/− mice. (B) Tfh cell, GC B cell, and S+ GC B cell absolute numbers, as detailed in A . (C) Absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and <t>Tlr7</t> −/− mice. (D) Frequencies and absolute numbers of Tfh cells and GC B cells, as detailed in A , in mice treated with isotype, anti-IL-1R, or anti-IL-18 mAb. (E) IFN-α levels 8 hours after immunization. Mice were treated with isotype or anti-IL-1R mAb. (F) IFN-α levels in WT and Irf3/7−/− mice 8 hours after immunization. (G) Frequency and absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Irf3/7−/− mice. In ( A-G ), mice received 3 μg of Spikevax; n = 6-10 mice per group from 2-3 independent experiments. An unpaired two-tailed Mann-Whitney U test was conducted.
    Human Tlr7 Dual Reporter Hek 293 Cells, supplied by InvivoGen, used in various techniques. Bioz Stars score: 93/100, based on 27 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human tlr7 dual reporter hek 293 cells/product/InvivoGen
    Average 93 stars, based on 27 article reviews
    human tlr7 dual reporter hek 293 cells - by Bioz Stars, 2026-03
    93/100 stars

    Images

    1) Product Images from "Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses"

    Article Title: Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

    Journal: Cell

    doi: 10.1016/j.cell.2025.11.023

    (A) Representative flow cytometry of Tfh cells, GC B cells, and Spike-specific GC B cells (S+) from wild type (WT) and Myd88 −/− mice. (B) Tfh cell, GC B cell, and S+ GC B cell absolute numbers, as detailed in A . (C) Absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Tlr7 −/− mice. (D) Frequencies and absolute numbers of Tfh cells and GC B cells, as detailed in A , in mice treated with isotype, anti-IL-1R, or anti-IL-18 mAb. (E) IFN-α levels 8 hours after immunization. Mice were treated with isotype or anti-IL-1R mAb. (F) IFN-α levels in WT and Irf3/7−/− mice 8 hours after immunization. (G) Frequency and absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Irf3/7−/− mice. In ( A-G ), mice received 3 μg of Spikevax; n = 6-10 mice per group from 2-3 independent experiments. An unpaired two-tailed Mann-Whitney U test was conducted.
    Figure Legend Snippet: (A) Representative flow cytometry of Tfh cells, GC B cells, and Spike-specific GC B cells (S+) from wild type (WT) and Myd88 −/− mice. (B) Tfh cell, GC B cell, and S+ GC B cell absolute numbers, as detailed in A . (C) Absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Tlr7 −/− mice. (D) Frequencies and absolute numbers of Tfh cells and GC B cells, as detailed in A , in mice treated with isotype, anti-IL-1R, or anti-IL-18 mAb. (E) IFN-α levels 8 hours after immunization. Mice were treated with isotype or anti-IL-1R mAb. (F) IFN-α levels in WT and Irf3/7−/− mice 8 hours after immunization. (G) Frequency and absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Irf3/7−/− mice. In ( A-G ), mice received 3 μg of Spikevax; n = 6-10 mice per group from 2-3 independent experiments. An unpaired two-tailed Mann-Whitney U test was conducted.

    Techniques Used: Flow Cytometry, Two Tailed Test, MANN-WHITNEY



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    (A) Representative flow cytometry of Tfh cells, GC B cells, and Spike-specific GC B cells (S+) from wild type (WT) and Myd88 −/− mice. (B) Tfh cell, GC B cell, and S+ GC B cell absolute numbers, as detailed in A . (C) Absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and <t>Tlr7</t> −/− mice. (D) Frequencies and absolute numbers of Tfh cells and GC B cells, as detailed in A , in mice treated with isotype, anti-IL-1R, or anti-IL-18 mAb. (E) IFN-α levels 8 hours after immunization. Mice were treated with isotype or anti-IL-1R mAb. (F) IFN-α levels in WT and Irf3/7−/− mice 8 hours after immunization. (G) Frequency and absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Irf3/7−/− mice. In ( A-G ), mice received 3 μg of Spikevax; n = 6-10 mice per group from 2-3 independent experiments. An unpaired two-tailed Mann-Whitney U test was conducted.
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    Image Search Results


    (A) Representative flow cytometry of Tfh cells, GC B cells, and Spike-specific GC B cells (S+) from wild type (WT) and Myd88 −/− mice. (B) Tfh cell, GC B cell, and S+ GC B cell absolute numbers, as detailed in A . (C) Absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Tlr7 −/− mice. (D) Frequencies and absolute numbers of Tfh cells and GC B cells, as detailed in A , in mice treated with isotype, anti-IL-1R, or anti-IL-18 mAb. (E) IFN-α levels 8 hours after immunization. Mice were treated with isotype or anti-IL-1R mAb. (F) IFN-α levels in WT and Irf3/7−/− mice 8 hours after immunization. (G) Frequency and absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Irf3/7−/− mice. In ( A-G ), mice received 3 μg of Spikevax; n = 6-10 mice per group from 2-3 independent experiments. An unpaired two-tailed Mann-Whitney U test was conducted.

    Journal: Cell

    Article Title: Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

    doi: 10.1016/j.cell.2025.11.023

    Figure Lengend Snippet: (A) Representative flow cytometry of Tfh cells, GC B cells, and Spike-specific GC B cells (S+) from wild type (WT) and Myd88 −/− mice. (B) Tfh cell, GC B cell, and S+ GC B cell absolute numbers, as detailed in A . (C) Absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Tlr7 −/− mice. (D) Frequencies and absolute numbers of Tfh cells and GC B cells, as detailed in A , in mice treated with isotype, anti-IL-1R, or anti-IL-18 mAb. (E) IFN-α levels 8 hours after immunization. Mice were treated with isotype or anti-IL-1R mAb. (F) IFN-α levels in WT and Irf3/7−/− mice 8 hours after immunization. (G) Frequency and absolute numbers of Tfh cells and GC B cells, as detailed in A , in WT and Irf3/7−/− mice. In ( A-G ), mice received 3 μg of Spikevax; n = 6-10 mice per group from 2-3 independent experiments. An unpaired two-tailed Mann-Whitney U test was conducted.

    Article Snippet: Human TLR7 Dual Reporter HEK 293 Cells , InvivoGen , Cat#hkd-htlr7.

    Techniques: Flow Cytometry, Two Tailed Test, MANN-WHITNEY